Links to documents:
Access this URL ([Link to copy hosted by North of Tyne Area Prescribing Committee ]
Download this file (Gender-Dysphoria-Feminising-Hormones-November-2014.pdf)Document[Archive copy hosted by UK Trans Info]

Brief Summary

Information for GPs regarding the use of feminising hormone therapy in gender dysphoria. This guidance has been prepared and approved for use in Newcastle, North Tyneside and Northumberland in consultation with the Primary and Secondary Care NHS trusts

Extract from Document

Gender dysphoria is a condition in which there is a psychological experience of oneself as a man or woman, which is incongruent with the individual’s external
sexual characteristics of the body. The individual’s physical sex is not aligned to their gender identity.

Sometimes, the distress/discomfort is sufficiently intense that people undergo transition from one point on a notional gender continuum to another – from Male-to-Female or Female-to-Male. This typically involves changes to social role and presentation, and may necessitate treatment with cross-sex hormones and/or having gender related surgery. In order to achieve this, hormones of the opposite biological sex are administered, sometimes in conjunction with medication to suppress endogenous sex hormone production. Gonadotrophin Releasing Hormone (GnRH) analogues are generally used in order to achieve this.

The aim of endocrine treatment is a physiological end organ response. This is based on the management of circulating hormone levels to allow accurate and individual dose titration to achieve suppression of hormone effects associated with the undesired gender. Treatment is flexible and patient-led according to the individuals needs as far as is consistent with clinical safety and the agreement of the prescriber.

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